Successfully navigating preclinical development requires expertise and biosimulation to ensure IND success. Certara enables scientists to predict human PK, optimize ADME, simulate drug interactions, and minimize animal studies.
We improve your success by proactively addressing CMC to avoid toxicity issues, planning your nonclinical studies, simulating ADME, predicting human PK from in vitro and animal studies, and assessing drug interactions, amongst many other preclinical tasks. For example, we predicted a First-In-Human dose 50-100X higher than traditional methods, reducing time on subtherapeutic doses and expediting development. Biosimulation can support your intellectual property by showcasing the distinctiveness of the drug’s mechanism of action.
